Does PPI Cause Weight Gain?

Does acid reflux medicine make you gain weight?

Thanks.

Yes, Nexium and other heartburn drugs may cause weight gain — as can other drugs, such as certain antidepressants, beta-blockers, and antihistamines.

You should talk to your doctor or pharmacist before starting any medication so you understand all the potential side effects of any drug you take..

What are the side effects of long term use of proton pump inhibitors?

They found that using a PPI for over 1 year increased the risk of a hip fracture by 44%. They also found that the risk increased further if the patients were taking the PPI a longer period of time, or at higher doses. This is probably due to impaired calcium absorption when there is less acid in the stomach.

Do proton pump inhibitors affect digestion?

PPIs impair the hydrolytic digestion by inhibiting acid-dependent peptic activity, thereby delaying the solid emptying. Gastric emptying of liquids largely depends on volume and energy density of intragastric contents.

Can omeprazole help you lose weight?

In contrast, the option of long-term PPI therapy was associated with a significant body weight gain in the present study. Omeprazole and other PPIs delay gastric emptying[6-9], which induces postprandial fullness, dyspeptic symptoms, gastrointestinal bacterial overgrowth, and subsequent weight loss[10,11].

Why can you only take omeprazole for 14 days?

Does Prilosec OTC work right away? Prilosec OTC starts to work on the very first day of treatment, but may take 1 to 4 days for full effect (although some people get complete relief within 24 hours). Taking Prilosec OTC every day for 14 days helps to ensure that acid production is consistently controlled.

Can omeprazole make you gain weight?

Check with your doctor right away if you or your child has a fever, joint pain, skin rash, swelling of the body, feet, or ankles, or unusual weight gain after receiving this medicine. These could be symptoms of a serious kidney problem called acute interstitial nephritis.